Conolidine’s analgesic results stem from its interaction with non-opioid pain pathways. In contrast to opioids, which bind to µ-opioid receptors in the central nervous technique, conolidine modulates alternate molecular targets. A Science Innovations study identified that conolidine interacts Using the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability. https://trentonbevnb.csublogs.com/46430738/an-unbiased-view-of-alternative-natural-pain-relief-to-replace-traditional-painkillers