Large glucose one-way links to dysfunctions of glucose uptake and catabolism and induces large oxidative stress, dysfunction of endothelial cells. Large hypertension brings about cardiac and vascular injury. Central obesity is linked to maldistribution of absolutely free fatty acid, overproduction of inflammatory molecules, and leptin resistance [21]. Title your collection: https://www.directivepublications.org/journal-of-cardiovascular-diseases/